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Acetaminophen/butalbital/caffeine is used in the treatment of headache and belongs to the drug class analgesic combinations. Risk cannot be ruled out during pregnancy. Acetaminophen/butalbital/caffeine 325 mg / 50 mg / 40 mg is not a controlled substance under the Controlled Substances Act (CSA).
Butalbital, acetaminophen, and caffeine combination is used to relieve symptoms of tension (or muscle contraction) headaches.
Butalbital belongs to the group of medicines called barbiturates. Barbiturates act in the central nervous system (CNS) to produce their effects.
Acetaminophen is used to relieve pain and reduce fever in patients. It does not become habit-forming when taken for a long time. But acetaminophen may cause other unwanted effects when taken in large doses, including liver damage.
When butalbital is used for a long time, it may become habit-forming, causing mental or physical dependence. However, people who have continuing pain should not let the fear of dependence keep them from using narcotics to relieve their pain. Physical dependence may lead to withdrawal side effects if treatment is stopped suddenly. However, severe withdrawal side effects can usually be prevented by gradually reducing the dose over a period of time before treatment is stopped completely.
Caffeine is a CNS stimulant that is used with pain relievers to increase their effect. It has also been used for migraine headaches. However, caffeine can also cause physical dependence when it is used for a long time. This may lead to withdrawal (rebound) headaches when you stop taking it.
This medicine is available only with your doctor’s prescription.
While Fioricet can be an effective and life-changing medication for people suffering from tension headaches, there is also the risk of Fioricet abuse or addiction. It’s important to consider the possible side effects and risks of using Fioricet to determine if this drug is right for you.
What is Fioricet?
People who suffer from tension headaches may receive a prescription of Fioricet. Fioricet includes three different drug ingredients that can help manage different symptoms of tension headaches. These include:
-
- Butalbital: A type of barbiturate that can help muscle relaxation.
- Acetaminophen: Also called paracetamol (sold as Tylenol) and helps to relieve pain.
- Caffeine: Enhances the effects of acetaminophen.
The ingredients of Fioricet help to address pain specifically or can help to enhance the effects of the painkillers. Some types of Fioricet include codeine, which is an opiate used to treat pain. This can increase the effect of Fioricet, but also increase some of the risks for misuse or addiction.
Is Fioricet a Controlled Substance?
Fioricet is a controlled substance, which means that it requires a prescription and cannot be purchased over the counter. Fioricet can only be prescribed a certain number of times following a Fioricet prescription schedule. This is to avoid abuse or dependence and to reduce the risk of addiction.
What Does Fioricet Look Like?
Fioricet comes in a pill or tablet form and is taken orally. It can also come as a liquid solution, but this is less common. The dose of the medication will be indicated on the tablet packaging or bottle.
Alternative Names for Fioricet
The combination of butalbital, acetaminophen and caffeine has been formulated by different pharmaceutical brands and can be known by different names in different places.
The combination of butalbital, acetaminophen and caffeine has been formulated by different pharmaceutical brands and can be known by different names in different places.
- Brand Names: The combination of butalbital, acetaminophen and caffeine is sold under other brand names, as well as Fioricet. These include Americet, Ezol and Alagesic among others.
- Generic Names: Fioricet may be referred to as the generic names of the drugs combination (butalbital, acetaminophen and caffeine)
- Street Names: There are few known street names for Fioricet that does not contain codeine, as it is lower risk for abuse and addiction. Barbiturates, a drug component of Fioricet, may be referred to simply as Barbs.
What is the most important information I should know about Fioricet (Acetaminophen, Butalbital, And Caffeine)?
Do not use this medicine if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.
You should not use acetaminophen, butalbital, and caffeine if you are allergic to it, if you have porphyria, or if you have recently used alcohol, sedatives, tranquilizers, or other narcotic medications.
To make sure acetaminophen, butalbital, and caffeine is safe for you, tell your doctor if you have:
-
- liver disease, cirrhosis, a history of alcoholism or drug addiction, or if you drink more than 3 alcoholic beverages per day;
- kidney disease;
- asthma, sleep apnea, or other breathing disorder;
- stomach ulcer or bleeding;
- a history of skin rash caused by any medication;
- a history of mental illness or suicidal thoughts; or
- if you use medicine to prevent blood clots.
It is not known whether this medicine will harm an unborn baby. If you use butalbital while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks. Tell your doctor if you are pregnant or plan to become pregnant.
This medicine can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
Drug Interactions
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Acepromazine
- Alfentanil
- Alprazolam
- Amobarbital
- Anileridine
- Aripiprazole
- Asenapine
- Baclofen
- Benperidol
- Benzhydrocodone
- Bromazepam
- Buprenorphine
- Buspirone
- Butabarbital
- Butorphanol
- Calcifediol
- Calcium Oxybate
- Cannabidiol
- Carbinoxamine
- Carisoprodol
- Carphenazine
- Chloral Hydrate
- Chlordiazepoxide
- Chlorpromazine
- Chlorzoxazone
- Clobazam
- Clonazepam
- Clorazepate
- Clozapine
- Codeine
- Cyclobenzaprine
- Dexmedetomidine
- Diacetylmorphine
- Diazepam
- Dichloralphenazone
- Difenoxin
- Dihydrocodeine
- Diphenhydramine
- Diphenoxylate
- Doxylamine
- Droperidol
- Enflurane
- Esketamine
- Estazolam
- Eszopiclone
- Ethchlorvynol
- Ethopropazine
- Ethylmorphine
- Fentanyl
- Flibanserin
- Flunitrazepam
- Fluphenazine
- Flurazepam
- Fluspirilene
- Fospropofol
- Gabapentin Enacarbil
- Halazepam
- Haloperidol
- Halothane
- Hexobarbital
- Hydrocodone
- Hydromorphone
- Hydroxyzine
- Isoflurane
- Ketamine
- Ketazolam
- Ketobemidone
- Levocetirizine
- Levorphanol
- Lorazepam
- Loxapine
- Magnesium Oxybate
- Meclizine
- Melperone
- Meperidine
- Mephobarbital
- Meprobamate
- Meptazinol
- Mesoridazine
- Metaxalone
- Methadone
- Methdilazine
- Methocarbamol
- Methohexital
- Methotrimeprazine
- Methylene Blue
- Midazolam
- Molindone
- Moricizine
- Morphine
- Morphine Sulfate Liposome
- Nalbuphine
- Nicomorphine
- Nitrazepam
- Nitrous Oxide
- Olanzapine
- Opium
- Opium Alkaloids
- Orlistat
- Orphenadrine
- Oxazepam
- Oxycodone
- Oxymorphone
- Papaveretum
- Paregoric
- Pentazocine
- Pentobarbital
- Perampanel
- Perazine
- Periciazine
- Perphenazine
- Phenobarbital
- Pimozide
- Piperacetazine
- Pipotiazine
- Piritramide
- Potassium Oxybate
- Prazepam
- Pregabalin
- Primidone
- Prochlorperazine
- Promazine
- Promethazine
- Propofol
- Quazepam
- Quetiapine
- Ramelteon
- Remifentanil
- Remimazolam
- Remoxipride
- Secobarbital
- Sertindole
- Sodium Oxybate
- Sufentanil
- Sulpiride
- Suvorexant
- Tapentadol
- Temazepam
- Thiethylperazine
- Thiopental
- Thiopropazate
- Thioridazine
- Tilidine
- Tizanidine
- Tolonium Chloride
- Topiramate
- Tramadol
- Triazolam
- Trifluoperazine
- Trifluperidol
- Triflupromazine
- Trimeprazine
- Zaleplon
- Zolpidem
- Zopiclone
- Zotepine
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Aluminum Carbonate, Basic
- Aluminum Hydroxide
- Aluminum Phosphate
- Dihydroxyaluminum Aminoacetate
- Dihydroxyaluminum Sodium Carbonate
- Ginkgo
- Magaldrate
- Magnesium Carbonate
- Magnesium Hydroxide
- Magnesium Oxide
- Magnesium Trisilicate
Other Interactions
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
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Other Medical Problems
The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
- Depression, history of or
- Lung or breathing problems (eg, respiratory depression) or
- Mood or mental changes, history of—Use with caution. May make these conditions worse.
- Kidney disease (eg, patients receiving dialysis)—Use with caution. The effects may be increased because of slower removal of the medicine from the body.
Is Fioricet Addictive?
While it seems like opioids get the bulk of the attention right now regarding prescription medication addiction, Fioricet is addictive. When people take Fioricet, they should be warned of the potential for Fioricet abuse and Fioricet addiction. It’s the butalbital that may be habit-forming in Fioricet, and if it contains codeine, that element may also be.
Butalbital is a central nervous system depressant, and it can sedate how a person feels pain. This is combined with the pain-relieving effects of acetaminophen, which works differently than the butalbital.
So how do Fioricet abuse and Fioricet addiction occur?
When someone is addictive to Fioricet, it usually begins as tolerance. With a drug tolerance someone takes the substance for a period of time, and then their body becomes used to it, so they need continuously higher doses to get the same effects.
A tolerance can be developed for butalbital as well as codeine if it’s contained in Fioricet. There is research that shows the average barbiturate addict may need to take 1500 mg of the drug to feel the effects they want. Unfortunately, people who are addicted to Fioricet also often take other opioids and narcotics either to amplify the effects of the Fioricet or when they run out of it to achieve the same effect.
What are the signs of Fioricet addiction?
- One of the first outward signs of Fioricet addiction is often when people start doctor shopping, meaning they try to go to multiple doctors to get more of the drug.
- People may be taking more doses of Fioricet for the treatment of recurring headaches.
- You may have not only a physical dependence but also a Fioricet addiction if you start to experience symptoms of withdrawal when you stop taking it or take a lower dosage.
- People who are addicted to Fioricet may feel like they can’t function normally without it.
- When you’re addicted to Fioricet, you may be obsessed with finding it and taking it.
While all addictions to prescription drugs are worrisome, with Fioricet, there is not only the concern of being addicted to the butalbital, but there are the risks of the acetaminophen component of the drug. Acetaminophen can cause liver damage or failure when high amounts are taken, and it can be an acute situation where it happens very suddenly. It’s important for people who take Fioricet to be aware of this.
Acute liver failure can occur in doses of more than 4,000 mg in a day.
In addition to the dangers of acetaminophen, with Fioricet abuse, there is the risk of overdosing on butalbital as well. Butalbital can cause respiratory depression and excessive sedation, so Fioricet addiction is dangerous in multiple ways.
If you or someone you know may have a Fioricet abuse problem, it’s important to seek professional help, because it’s an addiction that can very easily be dangerous or deadly.
Withdrawal from Fioricet
“Withdrawal symptoms of Fioricet occur when you stop taking this drug after becoming dependent upon it.”Withdrawal symptoms of Fioricet occur when you stop taking this drug after becoming dependent upon it. A physician will typically reduce your dosage slowly in order to minimize the withdrawal symptoms, rather than abruptly discontinuing your usage of Fioricet. You may also receive medication to help you taper off Fioricet. Withdrawal symptoms usually begin between 8 and 36 hours after your last dose and may last up to a week or two. Signs of an overdose on Fioricet include the following:
- Anxiety
- Breathing trouble
- Raised blood pressure
- Elevated body temperature
- Delirium
- Tiredness
- Headaches
- Increased heart rate
- Nausea
- Ringing in the ears
- Shaking
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